منابع مشابه
Spying on IgE receptor signaling
Plasma membrane organization and the potential role, or not, of lipid raft microdomains in signal transduction is a controversial topic. Cross-correlation fluorescent correlation spectroscopy (CC-FCS) shows promise as a new approach to rapidly probe protein-protein interactions in living cells during signal transduction. CC-FCS data from studies of IgE receptor signaling challenge models of lar...
متن کاملIgE RECEPTOR SIGNALING AND ASTHMA
Elevated IgE levels and increased IgE sensitization to allergens are central features of allergic asthma. IgE binds to the high affinity IgE receptor FcεRI on mast cells , basophils , and dendritic cells , and mediates the activation of these cells upon antigeninduced crosslinking of IgE-bound FcεRI. FcεRI activation proceeds through a network of signaling molecules and adaptor proteins and is ...
متن کامل1 IgE RECEPTOR SIGNALING AND ASTHMA
Elevated IgE levels and increased IgE sensitization to allergens are central features of allergic asthma. IgE binds to the high affinity IgE receptor FcεRI on mast cells , basophils , and dendritic cells , and mediates the activation of these cells upon antigeninduced crosslinking of IgE-bound FcεRI. FcεRI activation proceeds through a network of signaling molecules and adaptor proteins and is ...
متن کاملRole of IgE Low-Affinity Receptor (CD23) in Pathogenesis of Nasal Polyp
Background: Nasal polyps, a common clinical problem, are characterized by eosinophilic and mast cell inflammation. The role of allergy and IgE in pathogenesis of nasal polyps is still unclear. IgE receptors are important components of the immunological pathway in allergic and inflammatory diseases. Objective: To determine if the low affinity IgE receptor (CD23) is presented on nasal polyp tis...
متن کاملThe murine lymphocyte receptor for IgE. II. Characterization of the multivalent nature of the B lymphocyte receptor for IgE
The murine B lymphocyte Fc epsilon R is functionally multivalent. Radiolabeled rat IgE, when bound to the B cell Fc epsilon R will co-isolate with the Fc epsilon R on a rat IgE affinity column; examination of the affinity column eluate by SDS-PAGE reveals the component previously identified as the Fc epsilon R as well as E and L chains from IgE. At low levels of Fc epsilon R saturation, up to 3...
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ژورنال
عنوان ژورنال: Ensho
سال: 1983
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.3.3_281